- PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS
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Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
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Page/Page column 140
(2016/07/05)
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- N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF
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The invention provides novel compounds having the general formula: [insert formula (I)] and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X2, L, subscript m, X1, ring D, R1, and RN have the meaning as described
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Paragraph 0316-0317; 0320-0321
(2014/01/18)
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- Multi-gram synthesis of a nucleotide-competing reverse transcriptase inhibitor
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An efficient multi-gram synthesis of a nucleotide-competing reverse transcriptase inhibitor is reported. The synthesis features a chiral auxiliary-assisted alcohol resolution, a Mitsunobu reaction involving a carbamate, followed by a lithium-iodide exchange/Weinreb ketone synthesis tandem. These chemical transformations were optimized in order to increase the yield of the synthesis. The route is concluded by a late-stage palladium-catalyzed cyanation followed by a pyrimidine-2-one ring formation.
- Duplessis, Martin,Morency, Louis,James, Clint,Minville, Joannie,Deroy, Patrick,Morin, Sébastien,Thavonekham, Bounkham,Tremblay, Martin,Halmos, Ted,Simoneau, Bruno,Bousquet, Yves,Sturino, Claudio
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supporting information
p. 2303 - 2307
(2013/06/27)
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- Substituted 2-phenylpyridines as herbicides
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2-Phenylpyridines I an their salts, wherein R1to R17, X1-X3are as defined in the specification. The compounds are useful as herbicides, desiccants and defoliants.
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- 3-Pyridyl enantiomers and their use as analgesics
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The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula I: STR1 or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula I above which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.
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- Pyridine derivatives and the N-oxides thereof, and the use thereof as intermediates for the synthesis of plant protecting agents
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The compounds of the formula I STR1 in which A denotes N or N→O, Z denotes O or NH, R denotes H, (halo)alkyl, (halo)alkenyl, (halo)alkynyl or alkoxycarbonyl, R1 denotes hydrogen, halogen, amino, --NHOH, hydroxyl, (substituted) phenylazo or a ra
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