A new class of alkylsulfinyl thiazolides is described. These compounds show strong activity against hepatitis viruses
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Page/Page column 34
(2012/05/07)
Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication
We report the syntheses and activities of a wide range of thiazolides [viz., 2-hydroxyaroyl-N-(thiazol-2-yl)amides] against hepatitis B virus replication, with QSAR analysis of our results. The prototypical thiazolide, nitazoxanide [2-hydroxybenzoyl-N-(5-
Stachulski, Andrew V.,Pidathala, Chandrakala,Row, Eleanor C.,Sharma, Raman,Berry, Neil G.,Iqbal, Mazhar,Bentley, Joanne,Allman, Sarah A.,Edwards, Geoffrey,Helm, Alison,Hellier, Jennifer,Korba, Brent E.,Semple, J. Edward,Rossignol, Jean-Francois
experimental part
p. 4119 - 4132
(2011/08/05)
ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS
A new class of alkylsulfonyl-substituted thiazolide compounds is described. These compounds show strong activity against hepatitis virus.
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Page/Page column 79
(2009/04/24)
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