- Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells
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A number of coumarins exhibit interesting pharmacological activities and are therefore of therapeutic use. We report here the synthesis and the structural analysis of new N-substituted 4-amino-3-(2-methylbenzyl)coumarins (compounds 8a-8e) that present str
- Jacquot, Yves,Laios, Ioanna,Cleeren, Anny,Nonclercq, Denis,Bermont, Laurent,Refouvelet, Bernard,Boubekeur, Kamal,Xicluna, Alain,Leclercq, Guy,Laurent, Guy
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- Synthesis and Photophysical Properties of 1,4-Dihydro-2 H,5H-chromeno[4,3-D][1,3]oxazin-5-ones, and Derivatives Containing Tethered 1,2,3-Triazoles, from 4-Aminocoumarins
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A facile protocol for the unprecedented one-pot H 2 SO 4 -mediated hydroxymethylation/cyclative N, O -acetalization of 4-aminocoumarins to 1,4-dihydro-2 H,5 H -chromeno[4,3- d ][1,3]oxazin-5-ones, in moderate to good yields, was deve
- Brites, Nathan P.,Dilelio, Marina C.,Iglesias, Bernardo A.,Kaufman, Teodoro S.,Silveira, Claudio C.,Vieira, Larissa A.
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p. 2965 - 2976
(2019/07/22)
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- Microwave assisted synthesis of 4-aryl/alkylaminocoumarins
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4-Aryl and 4-alkylaminocoumarins were prepared by reaction of 4-hydroxycoumarin with amines under microwave irradiation in solvent-free conditions in good to excellent yields.
- Chavan, Abhijit P.
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p. 179 - 181
(2007/10/03)
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- A Novel Transformation of 4-Arylaminocoumarins to 6H-1-Benzopyranoquinolin-6-ones Under Vilsmeier-Haack Conditions
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4-Aryl and 4-alkylaminocoumarins 1 were prepared by reacting of 4-hydroxycoumarin and an appropriate amine.The reaction of 1 with phosphorousoxychloride/dimethylformamide led to 6H-1-benzopyranoquinoline-6-one derivatives 2 in very good yields, whi
- Tabakovic, K.,Tabakovic, I.,Ajdini, N.,Leci, O.
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p. 308 - 310
(2007/10/02)
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