2,6,9-Trisubstituted purine derivatives as protein A mimetics for the treatment of autoimmune diseases
A series of 9-substituted and 2,9-disubstituted 6-(3-aminophenylamino) purines were synthesized and evaluated for their ability to mimic protein A binding to human IgG antibody. The structure-activity relationship (SAR) demonstrates that the 6-(3-aminoani
Zacharie, Boulos,Fortin, Daniel,Wilb, Nicole,Bienvenu, Jean-Francois,Asselin, Michel,Grouix, Brigitte,Penney, Christopher
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p. 242 - 246
(2009/05/26)
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