Highly selective fluorescence imaging of zinc distribution in HeLa cells and Arabidopsis using a naphthalene-based fluorescent probe
2-(N,N-Dimethylamino)naphthalene-based probe 1 was found to exhibit a dramatic enhancement in fluorescence upon addition of Zn2+, but not with any other metal ions. Probe 1 as a chemoprobe enabled high-resolution fluorescence imaging of zinc ions in HeLa cells and Arabidopsis. This journal is
Lee, Ji Ha,Lee, Jin Hyeok,Jung, Sung Ho,Hyun, Tae Kyung,Feng, Mingxiao,Kim, Jae-Yean,Lee, Jae-Hong,Lee, Hoyeon,Kim, Jong Seung,Kang, Chulhun,Kwon, Ki-Young,Jung, Jong Hwa
Lanthanide luminescence sensing of copper and mercury ions using an iminodiacetate-based Tb(III)-cyclen chemosensor
The design, synthesis and photophysical evaluation of 1.Tb.Na, a Tb(III)-cyclen-based sensor, possessing a phenyl iminodiacetate-based receptor, for the selective detection of Cu(II) and Hg(II) ions in water is demonstrated. Sensitisation of the Tb(III)
McMahon, Brian K.,Gunnlaugsson, Thorfinnur
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p. 5406 - 5410
(2010/11/02)
Synthesis and evaluation of potential CT (computer tomography) contrast agents for bone structure and microdamage analysis
The design and synthesis of several novel X-ray contrast agents 1-3, developed for targeting bone structures, and in particularly microcracks in bones, using CT (Computer Tomography) detection is described. These contrast agents are based on the use of the well known triiodobenzene platform, which was conjugated into one or more phenyliminodiacetate moieties, which can be used to 'lock' onto bone matrices. Compounds 1-3 were all tested for their ability to visualise cracks in bone structures (bovine bones) using μ-CT imaging. The Royal Society of Chemistry 2006.
Parkesh, Raman,Gowin, Wolfgang,Lee, T. Clive,Gunnlaugsson, Thorfinnur
p. 3611 - 3617
(2008/09/19)
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