- 3-(2,3-DIHYDRO-1H-INDEN-5-YL)PROPANOIC ACID DERIVATIVES AND THEIR USE AS NRF2 REGULATORS
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The present invention relates to compounds of Formula (I), and Formula (II), wherein B is benzotriazolyl, phenyl, triazolopyridinyl, or -(CH2)2-triazolyl each of which may be unsubstituted or substituted by 1, 2, or 3 substituents independently chosen from -C1-3 alkyl, -O-C1-3 alkyl, CN, - (CH2)2-O-(CH2)2-OR4 and halo; and D is -C(O)OH, -C(O)NHSO2CH3, -SO2NHC(O)CH3, 5-(trifluoromethyl)-4H-1,2,4-triazol-2-yl, or tetrazolyl; and their use as NRF2 regulators.
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Page/Page column 64
(2018/06/30)
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- NRF2 REGULATORS
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The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.
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Page/Page column 64
(2017/01/02)
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- SYNTHESIS AND SOME PHYSICAL PROPERTIES OF PHENYL CYCLOHEXYL ETHYLENES.
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Some series of trans-1-(4-substituted phenyl)-2(trans-4-n-alkylcyclohexyl) ethylenes, which show nematic phases, were prepared. Their transition temperatures, birefringences and bulk viscosities were measured. Their properties are compared with those of o
- Takatsu,Takeuchi,Sato
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p. 255 - 266
(2007/10/02)
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