An Efficient and Practical Synthesis of Bicyclononane-2,4-diones
Cyclohexane-1,3-dicarboxylic anhydrides (IVa-c), prepared from isophthalic acids in several steps, were treated with diethyl magnesiomalonate and triethylamine to give 3-di(ethoxycarbonyl)acetylcyclohexanecarboxylic acids (Va-c) in good yields.Compounds V