- Derivatives of 2, 3, 6-trifluorophenols and a process for their preparation
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The present invention relates to compounds of the formula (1) STR1 where R is H, a straight-chain or branched alkyl radical with 1 to 6 carbons, a fluorinated straight-chain or branched alkyl radical with 1 to 6 carbons, a benzyl radical, or a benzyl radical substituted by an alkyl group or alkoxy group with 1 to 4 carbons each, or by halogen, X is H, Cl, Br or I, and X is different from R, and a process for their preparation.
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- Homolytic Reactions of Polyfluoroaromatic Compounds. Part 16. Competitive Phenylation of Polyfluorobenzenes
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Pairs of polyfluorobenzenes were allowed to compete for phenyl radicals generated by thermolysis of benzoyl peroxide at 80 deg C.From the relative yields of biaryl, and the yields of each biaryl formed upon arylation of each arene individually, the relative rates of attack of each site in each arene were deduced.Neither iron(III) benzoate nor trichloroacetic acid uniformly improved yields of biaryl, although in some cases the isomer distribution altered, when decomposition of benzoyl peroxide was carried out in the presence of such additives, to favour products of aryldehydrogenation or of aryldefluorination, respectively.Competition did not usually affect the distribution of attack of a particular arene, except when hexafluorobenzene was used, in which case greater selectivity of attack of the second arene occured.This suggested the formation of a 'stabilised' phenyl radical, and supported an earlier suggestion of species such as >; other evidence also supported the postulate.
- Allen, Kim J.,Bolton, Roger,Williams, Gareth H.
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p. 691 - 696
(2007/10/02)
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