- Synthesis, structural properties, and pharmacological evaluation of 2-(acylamino)thiophene-3-carboxamides and analogues thereof
-
We have previously reported the synthesis and the pharmacological characterization of a family of methyl 2-(acylamino)thiophene-3-carboxylates as GABAB positive allosteric modulators active both in vitro and in vivo. In the present work, we des
- Mugnaini, Claudia,Pedani, Valentina,Giunta, Daniela,Sechi, Barbara,Solinas, Maurizio,Casti, Alberto,Castelli, Maria Paola,Giorgi, Gianluca,Corelli, Federico
-
p. 1782 - 1793
(2014/01/06)
-
- STUDIES ON THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS. PART XII. PYRAZOLO-1,5-BENZODIAZOCINE-4,10-DIONE. A NEW RING SYSTEM
-
Treatment of N-(1-R-4-carboxypyrazol-5-yl)-2-aminobenzamides 2b,e with thionyl chloride afforded new pyrazolo-1,3-oxazinones 3b,e.When the amide group of compounds 2b,e was blocked pyrazolo-1,5-benzodiazocine-4,10-diones 6a,d were obtained.
- Plescia, Salvatore,Bajardi, Maria Luisa,Daidone, Giuseppe,Roccaro, Angela
-
p. 105 - 112
(2007/10/02)
-