The invention relates to a fenoxanil original drug synthesis method. The method includes: employing an organic solvent to synthesize an intermediate 2-(2, 4-dichlorophenoxy)propionic acid by one step, and then synthesizing fenoxanil. Therefore, the condensation yield reaches more than 96%. The method provided by the invention can substantially reduce wastewater and realize clean production, and has very good practical application effect.
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Paragraph 0007-0009
(2018/02/04)
Process for the manufacture of N-(1-cyanoalkyl)-2-phenoxypropionamide derivatives
The present invention provides an efficient, economic and ecologically sound process for the manufacture of a compound of formula I via the reaction of a suitable acid halide and an appropriate amine in the presence of aqueous carbonate or bicarbonate or a mixture thereof and optionally in the presence of a co-solvent. STR1
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(2008/06/13)
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