cas 116140-16-0, 6-Methyl-3-piperidinecarboxylic acid | Articles data ｜lookchem

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116140-16-0

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PYRIMIDINE COMPOUNDS THAT INHIBIT ANAPLASTIC LYMPHOMA KINASE
Compounds of Formula I are useful inhibitors of anaplastic lymphoma kinase. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
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Page/Page column 161

(2011/12/02)

FARNESYL PROTEIN TRANSFERASE INHIBITORS
Disclosed are compounds of formula (1.0), wherein R represents a cyclic moiety to which is bound an imodazolylalkyl group; R represents a carbamate, urea, amide or sulfonamide group; and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.
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Page/Page column 137

(2010/02/11)

Synthese et analyse conformationnelle de derives de l'acide nipecotique substitues par un reste methyle ou phenyle
The synthesis and conformational analysis of methyl- or phenyl substituted nipecotic acid are reported.A chair conformation is always observed.If the configuration does permit it both the carboxylic group and the hydrocarbon substituent adopt the equatorial orientation.If a diequatorial orientation is impossible, an axial orientation is observed for the carboxylic group.
Lapuyade, Gerard,Schlewer, Gilbert,Wermuth, Camille-Georges
p. 663 - 668
(2007/10/02)

More Articles about upstream products of 116140-16-0

3222-47-7
6-methylnicotinic acid

More Articles about downstream products of 116140-16-0

Chemical Properties

Boiling Point: 267.0±33.0 °C(Predicted)
Density: 1.062±0.06 g/cm3(Predicted)
PKA: 3.88±0.40(Predicted)
PSA: 49.33000
LogP: 0.78790

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