- Radioactive iodine marked Larotrectinib compound, and preparation method and application thereof
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The invention relates to a radioactive iodine marked Larotrectinib compound, and a preparation method and application thereof. The provided compounds comprise the radioactive iodine marked Larotrectinib compound with the following structural formula and a
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- BENZOXAZOLE CARBOXAMIDE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)
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A compound having the structure set forth in Formula (I) or Formula (II): wherein the variables Y, R1, R2, R3, and R4 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.
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Page/Page column 54
(2009/08/16)
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