- INVERSE ELECTRON DEMAND DIELS-ALDER REACTIONS OF 2,4,6-TRIS(ETHOXYCARBONYL)-1,3,5-TRIAZINE AND 2,4,6-TRIS(METHYLTHIO)-1,3,5-TRIAZINE: PYRIMIDINE INTRODUCTION
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A full investigation of the scope of the participation of 2,4,6-tris(ethoxycarbonyl)-1,3,5-triazine (la) and 2,4,6-tris(methylthio)-1,3,5-triazine (1b) in inverse electron demand Diels-Alder reactions suitable for the preparation of functionalized 5,6-disubstituted pyrimidines is detailed.The use of the resulting cycloadducts as immediate precursors to the parent 4,5-disubstituted pyrimidines is described.
- Boger, Dale L.,Dang, Qun
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p. 3379 - 3390
(2007/10/02)
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