- Synthesis of a reactive oxygen species responsive heterobifunctional thioketal linker
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A new heterobifunctional reactive oxygen species (ROS) responsive thioketal linker and its synthesis are described. This linker allows for developing new ROS-responsive agents with two distinct functionalities using universal bioconjugation methods. The reaction kinetics of the thioketal cleavage in the presence of ROS is also described.
- Ling, Xiaoxi,Zhang, Shaojuan,Shao, Pin,Wang, Pengcheng,Ma, Xiaochao,Bai, Mingfeng
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- Synthesis of thioketal connecting unit and application thereof in DNA sequencing
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The invention discloses synthesis of a thioketal connecting unit and application thereof in DNA sequencing. The connecting unit has a structural formula shown as the specification, wherein R=OH or COOH; R1=R2=methyl, or R1=phenyl, p-methoxyphenyl, 2, 4, 6
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Paragraph 0050-0055
(2017/05/23)
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- Thioketal connection unit, synthetic method and purpose thereof
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The invention discloses a thioketal connection unit, a synthetic method and a purpose thereof. The thioketal connection unit has a structure shown as a formula (I) in the specification, wherein, R=-OH or -COOH; R1 and R2 can satisfy one of the following c
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Paragraph 0065; 0066; 0067
(2017/01/02)
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