- PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF
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New compounds that bind to monoamine transporters are described. The compounds of the present invention can be racemic or pure R-or S-enantiomers. Certain preferred compounds of the present invention have a high selectively dopamine transporter versus the serotonin transporter. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter.
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Page/Page column 34; 35
(2008/06/13)
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- 2-heteroaryl-5,11-dihydro-6H-dipyrido?3,2-B:2',3'-E!?1,4!diazepines and their use in the prevention or treatment of HIV infection
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Novel compounds for the treatment of HIV-1 infection. These are 2-heteroary-5,11-dihydro-6H-dipyrido?3,2-b:2',3'-e!?1,4!diazepines of the formula STR1 wherein Z is oxygen, sulfur, =NCN or =NOR10 and Ar is a group of the formula I, II, III, IV or V STR2
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