Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic α3 β-tetrapeptides
Histone deacetylase (HDAC) inhibitors are powerful tools in understanding epigenetic regulation and have proven especially promising for the treatment of various cancers, but the discovery of potent, isoform-selective HDAC inhibitors has been a major chal
Olsen, Christian A.,Ghadiri, M. Reza
experimental part
p. 7836 - 7846
(2010/08/06)
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