Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors
A series of 2-(1-aryl-1H-imidazol-2-ylthio)acetamide [imidazole thioacetanilide (ITA)] derivatives were synthesized and evaluated as potent inhibitors of human immunodeficiency virus type-1 (HIV-1). Among them, the most potent HIV-1 inhibitors were 4a5 (E
Zhan, Peng,Liu, Xinyong,Zhu, Junjie,Fang, Zengjun,Li, Zhenyu,Pannecouque, Christophe,Clercq, Erik De
experimental part
p. 5775 - 5781
(2009/12/28)
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