Synthesis and Evaluation of the Pharmacological Activity of Rigid Analogues of Sympathomimetic Catecholamines Derived from Bicycloheptane
endo-3-Amino-exo-2-(3,4-dihydroxyphenyl)-2-hydroxybicycloheptane (4a) and its N-isopropyl derivatives (4b) were synthesized and assayed for their adrenergic activity on various isolated preparations.Compounds 4a and 4b, tested up to a dose of 10su
Balsamo, A.,Breschi, M. C.,Lapucci, A.,Macchia, B.,Macchia, F.,et al.
p. 856 - 859
(2007/10/02)
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