- Cyclic Amines
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The present invention is directed to novel cyclic amines which inhibit the P2X7 receptor.
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- HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS
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The invention relates to heterocyclic amide derivatives of formula (I), wherein R1, R2, R3, R4, n and X are as defined in the description, their preparation and their use as pharmaceutically active compounds.
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Page/Page column 48-49
(2014/08/07)
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- QUINOLINE OR ISOQUINOLINE SUBSTITUTED P2X7 ANTAGONISTS
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The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I)
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Page/Page column 21
(2009/12/05)
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