- COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS
-
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity.
- -
-
Page/Page column 38
(2012/03/27)
-
- COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS
-
The invention provides compounds of formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity. wherein: and the rest of the variables are as specified in the claims.
- -
-
Page/Page column 68
(2012/03/27)
-
- COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
-
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Ros, KDR, FMS, c-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-1R, ALK4, ALK5 and ALK or combinations thereof.
- -
-
Page/Page column 142
(2009/12/23)
-