Selective method for the preparation of isomeric N-alkyl and N-aryl-3(5)-amino-5(3)-hydroxy 1H-pyrazole-1-carboxamides
As part of a program to develop novel mechanism based skeletal muscle relaxants we identified 5-amino-3-hydroxy-1H-pyrazole-1-carboxyamide (1) as a potential structural lead. This highly functionalized pyrazole was prepared via a published procedure [1] (
Drummond,Johnson
p. 1123 - 1127
(2007/10/02)
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