Photoinduced Copper-Catalyzed Coupling of Terminal Alkynes and Alkyl Iodides
We have developed a photoinduced copper-catalyzed alkylation of terminal alkynes with primary, secondary, or tertiary alkyl iodides as electrophiles. The reaction has a broad substrate scope and can be successfully performed in the presence of ester, nitr
2,3-Dihydro-5-benzofuranols as antioxidant-based inhibitors of leukotriene biosynthesis
The enzymes that catalyze the oxidative metabolism of arachidonic acid have provided fertile ground for the development of useful therapeutic agents for nearly a quarter century. Inhibitors of the enzyme cyclooxygenase prevent the formation of the prostag