Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells
We developed histone deacetylase inhibitor (HDACI) prodrugs to enhance the expression of the external genes transfected into human cells with cationic nanoparticles (NPs). We synthesized five kinds of lipid-linked HDACI prodrugs in which n-dodecanoic acid
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