Oxidation of 1,2-Thiazoles: A Convenient Approach to 1,2-Thiazol-3(2H)-one 1,1-Dioxides
The 1,2-thiazoles obtained from 3-chloroalk-2-enals and ammonium thiocyanate (7-9, Scheme 1) are easily transformed to 1,2-thiazol-3(2H)-one 1,1-dioxides 10 on treatment with H2O2 in AcOH at 80 deg C.Hydrogenation of 10 in AcOH yields the corresponding sa