- Photoinduced DNA Interstrand Cross-Linking by Benzene Derivatives: Leaving Groups Determine the Efficiency of the Cross-Linker
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We have synthesized and characterized two small libraries of 2-OMe or 2-NO2-benzene analogues 2a-i and 3a-i containing a wide variety of leaving groups. Irradiation of these compounds at 350 nm generated benzyl radicals that were spontaneously oxidized to
- Fan, Heli,Peng, Xiaohua
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p. 493 - 506
(2020/12/22)
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- Mono and bis(bioreductive) alkylating agents: Synthesis and antitumor activities in a B16 melanoma model
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Several potentially bis(alkylating) bis(quinones) (3-5) and 1,4- and 1,3-bis(alkylating) monoquinones (6-13) belonging to general structure 2,2'-ethylenebis[5-[(leaving group) methyl]-1,4-benzoquinone] (3-5) and 2,5- and 2,6-bis[(leaving group)methyl]-1,4
- Witiak,Loper,Ananthan,Almerico,Verhoef,Filppi
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p. 1636 - 1642
(2007/10/02)
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