Application of the PIFA-mediated alkyne amidation reaction to the formal synthesis of (±)-clausenamide
The hypervalent iodine reagent PIFA promotes the intramolecular electrophilic cyclization of easily accessible N-aryl and N-methylalkynylamides leading to the formation of the pyrrolidinone skeleton in a very efficient way. This strategy has found applica
Tellitu, Imanol,Serna, Sonia,Dominguez, Esther
experimental part
p. 7 - 14
(2010/08/07)
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