Silver-Catalyzed C-H Trifluoromethylation of Arenes Using Trifluoroacetic Acid as the Trifluoromethylating Reagent
Direct trifluoromethylation of arenes using TFA as the trifluoromethylating reagent was achieved with Ag as the catalyst. This reaction not only provides a new protocol for aryl C-H trifluoromethylation, but the generation of CF3· from TFA may prove useful in other contexts and could potentially be extended to other trifluoromethylation reactions. (Chemical Equation Presented).
SYNTHESIS OF TEREPHTHALIC ACIDS CONTAINING POLYFLUOROALKYL GROUPS
The syntheses of new terephthalic acids (8a-d) containing various polyfluoroalkyl groups (a ; CF3, b ; HCF2, c ; H(CF2)3 and d ; H(CF2)5) are described in this paper.These compounds were obtained by aromatization (bromination and dehydrobromination) of Di