- Chemical and chemotaxonomical studies of ferns. LXXXI. Characteristic lignans of blechnaceous ferns
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Four lignans, blechnic acid (1), 7-epiblechnic acid (3), 8-epiblechnic acid (6) and brainic acid (2), were isolated from six Blechnaceous ferns, Blechnum orientale, Struthiopteris amabilis, S. niponica, Woodwardia orientalis, W. proilfera and Brainea insignis. Their structures were determined by spectroscopic methods and chemical conversion.
- Wada,Kido,Tanaka,Murakami,Saiki,Chen
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- Derivatives of 8-epiblechnic Acid and their Effects on Down-Regulation of Endothelin (ETA) receptor mRNA
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The present application discloses derivatives of 8-epiblechnic acid and use thereof in treating a disease related to endothelin receptor A or endothelin-1 (ET-1) over-expression, such as hypertension, cancer, atherosclerosis, and myocardial infarction.
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Page/Page column 3-4
(2010/03/31)
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- Reassignment of the configuration of salvianolic acid B and establishment of its identity with lithospermic acid B
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Salvianolic acid B and lithospermic acid B are the major components of Salvia miltiorrhiza, which is one of the most popular herbal traditional medicines in Asian countries. Salvianolic acid B and lithospermic acid B are reported to have identical structures except for the configurational assignments of two stereocenters. Through chemical correlation between a degradation product of salvianolic acid B and synthetic material, the absolute configuration of Salvianolic acid B has been corrected to establish that Salvianolic acid B and lithospermic acid B are in fact the same compound.
- Watzke, Anja,O'Malley, Steven J.,Bergman, Robert G.,Ellman, Jonathan A.
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p. 1231 - 1233
(2008/12/22)
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