- OXIDATIVE CYCLIZATION OF 2-AMINO-1-ARYLIDENEAMINOBENZIMIDAZOLES INTO 1,2,4-TRIAZOLOBENZIMIDAZOLES
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When heated in nitrobenzene, 1-arylideneamino-2-methylaminobenzimidazoles convert in a 20...30percent yield into 2-aryl-3-methyl-1,2,4-triazolobenzimidazoles.In addition, 2-methylaminobenzimidazole and the corresponding benzonitrile are formed as a result of thermal splitting of the N-N bond.Under the same conditions, 2-amino-1-arylideneaminobenzimidazoles and 1-arylideneamino-3-methylbenzimidazoline-2-imines give only products of splitting off of the nitrile.In several cases, the subsequent reaction of the nitrile with 2-amino-1-methylbenzimidazole leads to the formation of benzamidines.
- Kuz'menko, T. A.,Kuz'menko, V. V.,Pozharskii, A. F.,Klyuev, N. A.
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p. 1012 - 1017
(2007/10/02)
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