Direct asymmetric aldol reaction of acetone with α-ketoesters catalyzed by primary-tertiary diamine organocatalysts
Novel primary-tertiary diamine organocatalysts derived from l-serine were utilized to promote enantioselective aldol reaction of acetone with α-ketoesters. The desired products were obtained in high yields and with good to excellent enantioselectivities (up to 95% ee).
Jiang, Zhaoqin,Lu, Yixin
supporting information; experimental part
p. 1884 - 1886
(2010/09/07)
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