Secondary β-Aminobenzamide and Heteroatom Directed Lithiation in the Synthesis of 5,6-Dimethoxyanthanilamides and Related Compounds
Directed ortho-lithiation strategies have been applied in the synthesis of the dopamine D-2 antagonist (S)-6-amino-5-bromo-2,3-dimethoxy-N-benzamide (NCQ 318).The secondary β-amino side chain was found to be a powerful orth
Bengtsson, Stefan,Hoegberg, Thomas
p. 4549 - 4553
(2007/10/02)
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