- PhenoFluorMix: Practical chemoselective deoxyfluorination of phenols
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A practical deoxyfluorination with novel deoxyfluorinating reagent PhenoFluorMix, a mixture of N,N'-1,3-bis(2,6-diisopropylphenyl)chloroimidazolium chloride and CsF, is presented. PhenoFluorMix overcomes the challenges associated with hydrolysis of PhenoFluor. PhenoFluorMix does not hydrolyze, is readily available on decagram scale, and is storable in air. In this paper, we demonstrate the practicality of the reagent and exhibit the deoxyfluorination of a variety of phenols and heterocycles.
- Fujimoto, Teppei,Ritter, Tobias
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- Neutral Nickel(II) Complexes Bearing Aryloxide Imidazolin-2-imine Ligands for Efficient Copolymerization of Norbornene and Polar Monomers
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A series of novel aryloxide imidazolin-2-imine bidentate neutral Ni(II) complexes with different substituents on the imidazolin-2-imine ligand were synthesized and characterized. The complex Ni2 bearing a 2,6-diisopropylphenyl substituent adopted an almost square planar geometry, while the bulkier 2,6-bis(diphenylmethyl)-4-methylphenyl substituent ligated complex Ni3 was obtained in an allyl adduct base-free η3 coordination mode. In the presence of B(C6F5)3, these Ni(II) complexes exhibited remarkably high activity (up to 2.7 × 107 g of PNB (mol of Ni)-1 h-1) and particularly good thermal stability toward the addition polymerization of norbornene. Most importantly, these catalysts were able to promote the direct copolymerization of norbornene with various polar monomers with high activity (~105 g (mol of Ni)-1 h-1), reasonable comonomer incorporation (0.14-3.08%), and high copolymer molecular weight (Mn up to 2.0 × 105). The strategy of installing a strongly electron donating imidazolin-2-imine ligand on the nickel complex demonstrates a great advantage for the copolymerization of an olefin with polar monomers.
- Li, Mingyuan,Cai, Zhengguo,Eisen, Moris S.
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p. 4753 - 4762
(2019/01/04)
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- PhenoFluor: Practical synthesis, new formulation, and deoxyfluorination of heteroaromatics
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We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.
- Fujimoto, Teppei,Becker, Fabian,Ritter, Tobias
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p. 1041 - 1044
(2014/11/07)
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- FLUORINATION OF ORGANIC COMPOUNDS
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Methods for fluorinating organic compounds are described herein.
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Page/Page column 20-21
(2012/11/06)
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- Deoxyfluorination of phenols
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An operationally simple ipso fluorination of phenols with a new deoxyfluorination reagent is presented.
- Tang, Pingping,Wang, Weike,Ritter, Tobias
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supporting information; experimental part
p. 11482 - 11484
(2011/10/02)
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- Synthesis of 4- and 4,5-functionalized imidazol-2-ylidenes from a single 4,5-unsubstituted imidazol-2-ylidene
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Using the nucleophilicity of NHCs and a NHCs, as well as the leaving group ability of the former, the carbon-carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.
- Mendoza-Espinosa, Daniel,Donnadieu, Bruno,Bertrand, Guy
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supporting information; experimental part
p. 7264 - 7265
(2010/08/05)
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