NOVEL INTERMEDIATES FOR PRODUCING [R-(E)]-1-[[[1-[3-[2-(7- CHLORO -QUINOLINYL)ETHENYL]PHENYL]-3-[2-(1-HYDROXY- METHYLETHYL) PHENYL]PROPYL]THIO] METHYL] CYCLOPROPANEACETIC ACID, MONOSODIUM SALT AND PROCESS THEREOF
Disclosed herein are novel intermediates for producing [R-(E)]-1-[[[1-[3-[2-(7- chloro-2-quinolinyl)ethenyl]phenyl] -3 - [2-(1-hydroxy- 1 -methylethyl) phenyl] propyl]thio] methyl] cyclopropaneacetic acid, monosodium salt (montelukast sodium). Further the invention provides processes for preparing said intermediates.
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Page/Page column 7; 12; 20; 24-25
(2010/06/20)
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