Synthesis of Pyranoindoles as Conformationally Restricted Analogues of the Serotonin Antagonist ICS 205-930 and as Precursors to 2-Vinylindoles
A useful synthesis of some pyranoindoles is described that allows access to conformationally restricted analogues of the serotonin (5HT3) antagonist, ICS 205-930.These pyranoindoles can be converted in one step to 2-vinylindole derivatives.
Macor, John E.,Ryan, Kevin,Newman, Michael E.
p. 4785 - 4795
(2007/10/02)
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