Regiospecific cyclization of 4-alkoxyvinyl trifluoro[chloro]methyl ketones with 6-trifluoro[chloro]methyl-2-hydrazine pyrimidines. A convenient method to obtain trifluoro[chloro]methylated 2-(5-hydroxy-5-trifluoro[chloro]methyl-4,5-dihydro-1H-pyrazol-1-yl]- pyrimidines
The regiospecific synthesis of a novel series of 4-trifluoro[chloro]-2- (5-hydroxy-5-trifluoro[chloro]methyl-4,5-dihydro-1H-pyrazol-1-yl]-pyrimidines from the reactions of 4-alkoxy-1,1,1-trifluoro[chloro]-alk-3-en-2-ones with 6-trifluoro[chloro]methyl-2-hydrazine pyrimidines is presented.
Zanatta, Nilo,Flores, Darlene C.,Madruga, Claudia C.,Faoro, Debora,Flores, Alex F. C.,Bonacorso, Hello G.,Martins, Marcos A. P.
p. 894 - 898
(2007/10/03)
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