- SYNTHETIC DERIVATIVES OF CHOLIC ACID 7-SULFATE AND USES THEREOF
-
The compositions and methods provided herein are related, in part, to the discovery of cholic acid 7-sulfate as a treatment for diabetes. Provided herein is a method for treating a metabolic disorder (e.g., diabetes, obesity), or an inflammatory disease (e.g., Crohn's disease, inflammatory bowel disease, ulcerative colitis, pancreatitis, hepatitis, appendicitis, gastritis, diverticulitis, celiac disease, food intolerance, enteritis, ulcer, gastroesophageal reflux disease (GERD), psoriatic arthritis, psoriasis, and rheumatoid arthritis) in a subject in need thereof comprising administering to a subject a compound of Formulae (I)-(XVII).
- -
-
Paragraph 00367-00368
(2020/07/05)
-
- Cationic heteroleptic cyclometalated iridiumIII complexes containing phenyl-triazole and triazole-pyridine clicked ligands
-
Novel heteroleptic iridium complexes containing the 1-substituted-4-phenyl- 1H-1,2,3-triazole (phtl) cyclometalating ligand have been synthesized. The 3+2 Huisgen dipolar cycloaddition method ('click' chemistry) was utilized to prepare a class of bidentat
- Felici, Marco,Contreras-Carballada, Pablo,Smits, Jan M. M.,Nolte, Roeland J. M.,Williams, Rene M.,De Cola, Luisa,Feiters, Martin C.
-
experimental part
p. 2039 - 2059
(2010/05/18)
-