- TREATMENT OF CD151 RELATED DISORDERS
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The present invention relates to a method of treating a condition in a human related to CD151 the method comprising administering a therapeutically effective amount of a compound of Formula (I):
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Paragraph 0246; 0249
(2022/02/09)
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- METHOD OF TREATMENT OF CYTOMEGALOVIRUS
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The present invention relates to a method of prophylaxis or treatment of Cytomegalovirus infection in a subject the method comprising administering to the subject a therapeutically effective amount of a compound of Formula (I):
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Paragraph 0239; 0242
(2022/02/09)
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- METHODS OF PROPHYLAXIS AND TREATMENT OF CORONA VIRUS
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The present invention relates to a method of prophylaxis or treatment of Corona virus infection in a subject the method comprising administering to the subject a therapeutically effective amount of a compound of Formula (I):
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Paragraph 0248; 0251
(2022/02/09)
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- COMPOUNDS
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The present invention relates to compounds of formula (I) that have the ability to inhibit CD151.
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Paragraph 0242; 0245
(2022/02/09)
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- TREATMENT OF VETERINARY CONDITIONS ASSOCIATED WITH CD151
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The present invention relates to a method of treating a condition related to CD151 in a non-human animal, the method comprising administering a therapeutically effective amount of a compound of Formula (I): Formula (I)
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Paragraph 0245
(2022/02/09)
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- SUBSTITUTED PYRAZOLO-PYRIMIDINES AND USES THEREOF
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The present disclosure provides compounds that are inhibitors of PIKfyve kinases useful for the treatment of neurological diseases treatable by inhibition of PIKfyve. Also provided are pharmaceutical compositions containing such compounds, and methods of
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Paragraph 0175; 0178; 0179; 0250; 0253; 0254
(2021/07/24)
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- DUAL KINASE-BROMODOMAIN INHIBITORS
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Provided herein are compounds of Formula (I) that are dual inhibitors of kinases and bromo-domain proteins. The disclosure also relates to pharmaceutical compositions containing such compounds, methods for using such compounds in the treatment of cancers, particularly, the treatment of multiple myeloma cancers, and to related uses.
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Page/Page column 108; 222
(2021/12/12)
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- PYRAZOLO-PYRIMIDINE COMPOUNDS
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The present invention has searched for a variety of compounds which show IL-12/IL-23 production-inhibitory activities and herein provides a pharmaceutical composition and an agent for preventing or treating IL-12/IL-23 excess production-related diseases, which comprise the compound.
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Page/Page column 44
(2011/12/13)
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- PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS
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The present invention relates to a compound represented by formula [I]: wherein: R1 is hydrogen, halogen, lower alkyl or cyano; Ring A is an optionally substituted heterocyclic group; Ring B is an optionally substituted 3 to 6-membered monocyclic group; and Y is optionally substituted amino, optionally substituted cyclic amino, optionally substituted aliphatic 3 to 6-membered monocyclyloxy, optionally substituted lower alkyl or optionally substituted lower alkyl-O-, or a pharmaceutically acceptable salt thereof, and to their use as PDE10 inhibitor.
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Page/Page column 68
(2011/09/30)
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