Development of antiproliferative phenylmaleimides that activate the unfolded protein response
The current paper presents the synthesis and evaluation of a series of maleimides that were designed to inhibit the Cdc25 phosphatase by alkylation of catalytically essential cysteine residues. Although in HepB3 cell culture assays the analogues did exhib
Muus, Ulrike,Hose, Curtis,Yao, Wei,Kosakowska-Cholody, Teresa,Farnsworth, David,Dyba, Marzena,Lountos, George T.,Waugh, David S.,Monks, Anne,Burke Jr., Terrence R.,Michejda, Christopher J.
supporting information; experimental part
p. 4535 - 4541
(2010/08/22)
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