Synthesis and antimicrobial activities of two novel amino sugars derived from chloraloses
The synthesis of 5-amino-5-deoxy-1,2-O-(S)-trichloroethylidene-β-l-arabinofuranose and 6-amino-6-deoxy-1,2-O-(S)-trichloroethylidene-α-d-glucofuranose is described by a simple three- or four-step route. Antibacterial potency of the new compounds was determined using an inhibition zone diameter test. The results show that these compounds have a broad-spectrum activity against Gram-positive, Gram-negative bacteria and Candida albicans.
Yenil, Nilguen,Ay, Emriye,Ay, Kadir,Oskay, Mustafa,Maddaluno, Jacques
experimental part
p. 1617 - 1621
(2010/08/20)
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