- Chalcones: A new class of antimitotic agents
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A series of chalcones was evaluated as antimitotic agents. One of these, (E)-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methyl-2-propen- 1-one) (73), was found to be an effective antimitotic agent at a concentration of 4 nM in an in vitro HeLa
- Edwards,Stemerick,Sunkara
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p. 1948 - 1954
(2007/10/02)
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- Pyrrolidines
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Compounds represented by the formula SPC1 Wherein R1 is a pyridyl, R2 is hydrogen or lower alkyl, R3 is hydrogen, lower alkyl or benzyl and R4 is phenyl or phenyl substituted at one or more carbon atoms with one or more of halogen, lower alkyl, lower alkoxy, nitro or amino and pharmaceutically acceptable acid addition salts thereof, having analgesic activity are disclosed.
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