Preparation and utility of 5-β-D-ribofuranosyl-1H-tetrazole as a key synthon for C-nucleoside synthesis
A synthesis of 5-β-D-ribofuranosyl-1H-tetrazole (2) and 5-β-D- ribofuranosyl-l,3,4-oxadiazole-2(3H)-one (9) derivatives is described. Ring transformations of 2 have been investigated in an effort to establish the stability of this synthon for further use
Kobe,Prhavc,Hohnjec,Townsend
p. 2209 - 2244
(2007/10/02)
Novel regioselective N-alkylations of 5-substituted-2H-tetrazoles
Regioselective alkylation of 5-substituted-2H-tetrazoles 1 to 2-alkyl derivatives 3 was achieved via decarboxylative alkylation with alkyl cyanoformates. Lesser selectivity was observed with chloroformates.
Prhavc,Kobe
p. 1925 - 1928
(2007/10/02)
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