- New version of multicomponent condensation leading to 3-amino-2-acyl-4,5,6-trimethylthieno[2,3-b]pyridines
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3-Amino-2-acyl-4,5,6-trimethylthieno[2,3-b]pyridines were synthesized by multicomponent condensation of acetaldehyde, cyanothioacetamide, 4-(but-2-en-2-yl)-morpholine, and a-haloketones.
- Dyachenko
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p. 1578 - 1583
(2015/12/30)
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- Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors
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Cdc7 kinase plays a critical role in the regulation of DNA replication in eukaryotic cells and has been proposed as a target for cancer therapy. We have identified a class of Cdc7/Dbf4 inhibitors with a pyrido-thieno-pyrimidine core structure. Synthesis o
- Zhao, Chunlin,Tovar, Christian,Yin, Xuefeng,Xu, Qui,Todorov, Ivan T.,Vassilev, Lyubomir T.,Chen, Li
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scheme or table
p. 319 - 323
(2011/02/26)
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- Convenient synthesis of 2-pyridyl thioglycosides
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A reported method for preparation of a new class of pyridine thioglycosides via reaction of pyridine-2(1H)-thiones with 2,3,4-tri-O-acetyl-α-D-xylo- and -β-D-arabinopyranosyl bromides has been studied.
- Elgemeie, Galal,Eltamny, Elsayed,Elgawad, Ibraheim,Mahmoud, Nashwa
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body text
p. 473 - 475
(2009/08/15)
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- REACTIONS OF 2-CYANOTHIOACETAMIDE WITH α-ALKYLATED β-DIKETONES: SYNTHESIS OF PYRIDINE-2(1H)-THIONE, THIENOPYRIDINE AND PYRIDOPYRAZOLE DERIVATIVES
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A novel synthesis of pyridine-2(1H)-thiones, thienopyridines and pyridopyrazoles utilizing 2-cyanothioacetamide and α-alkylated β-diketones as starting components is described.
- Elgemeie, Galal E. H.,Ali, Hosny A.,Eid, Mohga M.
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p. 1517 - 1532
(2007/10/02)
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