- Pyrazolo-pyrrolo-pyrimidine-diones
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New pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of formula (I), STR1 where R1, R2, R3, R4 and m are as defined in the specification, e.g., 4-(benzoylmethyl)-6-cyclohexyl-6,7-dihydro-2-phenyl-4H-pyrazolo[1
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- Synthesis and Hypocholesterolemic Activity of 6,7-Dihydro-4H-pyrazolopyrrolopyrimidine-5,8-diones, Novel Inhibitors of AcylCoA:Cholesterol O-Acyltransferase
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A novel series of 6,7-dihydro-4H-pyrazolopyrrolopyrimidine-5,8-dione inhibitors of the enzyme acylCoA:cholesterol O-acyltransferase is described.A number of these derivatives were found to be potent modulators of serum lipoprotein levels in
- Larsen, Scott D.,Spilman, Charles H.,Bell, Frank P.,Dinh, Dac M.,Martinborough, Esther,Wilson, Gracella J.
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p. 1721 - 1727
(2007/10/02)
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