Quantitative Structure-Activity Relationship Analysis of Cation-Substituted Polyaromatic Compounds as Potentiators (Amplifiers) of Bleomycin-Mediated Degradation of DNA
A set of 21 polyheteroaromatic compounds substituted with flexible cationic groups and of similar molecular size has been analyzed for binding with DNA and for effects on the bleomycin-mediated degradation of the DNA double helix.Increases in apparent rat
Strekowski, Lucjan,Wilson, W. David,Mokrosz, Jerzy L.,Mokrosz, Maria J.,Harden, Donald B.,et al.
p. 580 - 588
(2007/10/02)
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