- Synthesis and antibacterial and antifungal evaluation of some chalcone based sulfones and bisulfones
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Two series of chalcone based sulfone and bisulfone derivatives were synthesized using chalcone, thiophenol and sodium metal at room temperature, followed by oxidation of chalcone sulfides with m-CPBA at 0 °C in a novel method. Both sulfones and bisulfones
- Konduru, Naveen Kumar,Dey, Sunita,Sajid, Mohammad,Owais, Mohammad,Ahmed, Naseem
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- KF/Al2O3-mediated Michael addition of thiols to electron-deficient olefins
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Potassium fluoride supported on alumina efficiently catalyzes Michael addition of aromatic and aliphatic thiols to a variety of conjugated alkenes such as α,β-unsaturated carbonyl compounds, carboxylic esters, amides, nitriles and chalcones. The Michael adducts are produced in good to excellent yields and relatively in short times. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency. Copyright Taylor & Francis, Inc.
- Moghaddam, F. Matloubi,Bardajee, G. Rezanejade,Veranlou, R. Oftadeh Chadorneshine
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p. 2427 - 2433
(2007/10/03)
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- Conjugate addition of indoles and thiols with electron-deficient olefins catalyzed by Bi(OTf)3
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Conjugate addition of indoles and thiols with a variety of electron-deficient olefins mediated by a catalytic amount of Bi(OTf)3 at ambient temperature to afford the corresponding Michael adducts in good to excellent yields with high selectivity is reported.
- Alam, M. Mujahid,Varala, Ravi,Adapa, Srinivas R.
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p. 5115 - 5119
(2007/10/03)
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