- Synthesis and antibacterial evaluation of novel 2-[N-Imidoylpyrrolidinyl] carbapenems
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The synthesis, antibacterial activity and DHP-susceptibility of a series of novel carbapenems, directly linked with heterocyclic moiety are described. Especially, the compounds linked pyrrolidine-carbapenem exhibited to have a good antibacterial activity against Staphylococcus aureus (MRSA) as well as Pseudomonas aeruginosa to maintain a good stability towards DHP-I.
- Hattori, Kouji,Yamada, Akira,Kuroda, Satoru,Chiba, Toshiyuki,Murata, Masayoshi,Sakane, Kazuo
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- NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF
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Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
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Paragraph 0957-0958
(2021/02/19)
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