Counterion-mediated hydrogen-bonding effects: Mechanistic study of gold(I)-catalyzed enantioselective hydroamination of allenes
Two of a kind: A new type of counterion-mediated syn-addition mechanism has been presented in gold-catalyzed enantioselective hydroamination reactions with [(R)-binap(AuOPNB)2] (OPNB=para-nitrobenzoate). A combination of both hydrogen bonding and the N-Au interaction efficiently controlled the challenging enantioselectivity of allenes.
Kim, Ji Hye,Park, Sung-Woo,Park, Sae Rom,Lee, Sungyul,Kang, Eun Joo