- Ethyl imidazole-1-carboxylate (EImC) as a carbonylating agent: Efficient synthesis of oxazolidin-2-ones from amino alcohols
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Various substituted oxazolidin-2-ones were synthesized from the corresponding amino alcohols using ethyl imidazole- 1-carboxylate (EImC). Highly substituted and sterically hindered amino alcohols and amino alcohols having a free hydroxy group were cyclized to oxazolidin-2-ones efficiently. This method is simple and produces oxazolidin-2-ones in very good yield.
- Veeraswamy,Reddy, K. Indrasena,Ragavan, R. Venkat,Yennam, Satyanarayana,Jayashree
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- Synthesis and antibacterial activities of chiral 1,3-oxazinan-2-one derivatives
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We report here the design, synthesis, and antibacterial activities of novel classes of compounds containing chiral 1,3-oxazinan-2-ones and oxazolidinones as the basic core structures. These compounds are tertiary amines containing the core structures and
- Wang, Guijun,Ella-Menye, Jean-Rene,Sharma, Vibha
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- TRI-CYCLE COMPOUND AND APPLICATIONS THEREOF
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Disclosed in the present invention are a compound represented by formula (I), a tautomer thereof or a pharmaceutically acceptable salt, and applications thereof in the preparation of drugs for treating HBV-related diseases.
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Paragraph 0354-0355; 0357
(2020/01/22)
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- A kind of IDO inhibitor and use thereof
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The embodiment of the invention provides general formula (I) compound or its pharmaceutically acceptable salts, stereoisomers, a tautomeric form each other, polymorphs, solvate, prodrug, metabolite or isotope derivatives, wherein the substituents R1
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Paragraph 0612-0613; 0619-0620
(2019/07/11)
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- 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES
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The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.
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Page/Page column 304; 305
(2016/07/05)
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- PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF
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A process for preparing N-(substituted)-C-- (substituted methyl)-oxazolidinones, C-(substituted methyl)-oxazolidinones, and N-(substituted)-C-- (substituted ethyl)-oxazolidinones, preferably chiral, from optically active C-(protected oxymethyl)- oxazolidi
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