- CATALYTIC RADIOFLUORINATION
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One aspect of the present invention relates to a method of preparing radio fluorinated substituted alkyl, cycloalkyl, aryl, and alkenyl compounds. In a preferred embodiment, potassium fluoride-18 is used. Another aspect of the invention relates to arylammonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the ammonium compound is a tetraaryl ammonium salt. Another aspect of the invention relates to arylsulfonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the sulfonium compound is a triaryl sulfonium salt. Another aspect of the present invention relates to a method of obtaining a positron emission image of a mammal, comprising the steps of administering to a mammal a compound of the invention, and acquiring a positron emission spectrum of the mammal.
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Page/Page column 92
(2010/11/30)
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- Chiral phosphines
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Novel substituted diphenyl tertiary phosphines of a pyrrolidine carboxylic acid derivative and their use as catalysts in the enantioselective hydrogenation of α-keto-β,β-dimethyl-γ-butyrolactone.
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