- Total Synthesis of the Second Messenger Analogue D-myo-Inositol 1- Phosphorothioate 4,5-Biphosphate: Optical Resolution of DL-1-O-Allyl-2,3,6-tri-O-Benzyl-myo-inositol and Fluorescent Labelling of myo-Inositol 1,4,5-Triphposphate
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Two routes for the synthesis of the myo-inositol 1,4,5-triphosphate analogue myo-inositol 1-phosphorothioate 4,5-bisphosphate have been devised.DL-2,3,6-Tri-O-benzyl-1-O-(cis-prop-1-enyl)-myo-inositol was prepared from DL-1-O-allyl-2,3,6-tri-O-benzyl-myo-
- Lampe, Dethard,Mills, Stephen J.,Potter, Barry V. L.
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p. 2899 - 2906
(2007/10/02)
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- Synthesis of myo-Inositol 1-Phosphorothioate 4,5-Bisphosphate: Preparation of a Fluorescently Labelled myo-Inositol 1,4,5-Trisphosphate Analogue
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Synthesis of myo-inositol 1-phosphorothioate 4,5-bisphosphate, a novel analogue of the second messenger myo-inositol 1,4,5-trisphosphate allows, for the first time, the attachment of a fluorescent reporter group at the 1-position.
- Lampe, Dethard,Potter, Barry V. L.
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p. 1500 - 1501
(2007/10/02)
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